JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2004, 53(4):192-196

Analysis of Tablets Containing the Antihistamine Loratadine: A Contribution to theIdentification of Impurities

N. Issa, M. Mlynárová
Štátny ústav pre kontrolu liečiv, Bratislava

Thin-layer chromatography on silica gel (Merck) was employed to examine potential impuritiespresent in loratadine-containing tablets. A method usable for testing of impurities was elaborated,which suitably supplements the determination of loratadine content using the spectrophotometricmethod in the UV region. The method was validated for selected pharmaceuticals.

Keywords: laratadine; thin-layer chromatography (TLC); impurities; validation

Published: April 1, 2004  Show citation

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Issa N, Mlynárová M. Analysis of Tablets Containing the Antihistamine Loratadine: A Contribution to theIdentification of Impurities. Čes. slov. farm. 2004;53(4):192-196.
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