JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2007, 56(4):159-164

Applications of molecularly imprinted polymers in analytical and pharmaceutical chemistry

M. Lachová1, J. Lehotay1, J. Čižmárik2
1 Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic
2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava Slovak Republic

The paper reviews recent developments in the use of molecularly imprinted polymers in several analytical techniques, such as solid-phase extraction, liquid chromatography, capillary electrophoresis, capillary electrochromatography, and as selective sorbents in chemical sensors. Molecular imprinting is achieved by the interaction between complementary groups in a template molecule and functional monomer units. The benefits of imprinted polymers are low cost, storage stability, high mechanical strength, repeated operations without loss of activity, and potential application to a wide range of target molecules.

Keywords: molecularly imprinted polymers; solid-phase extraction; liquid chromatography; electrochromatography; membranes; sensors

Received: April 23, 2007; Accepted: May 11, 2007; Published: April 1, 2007  Show citation

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Lachová M, Lehotay J, Čižmárik J. Applications of molecularly imprinted polymers in analytical and pharmaceutical chemistry. Čes. slov. farm. 2007;56(4):159-164.
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