JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2007, 56(2):85-89

An orientational examination of the effects of extracts from mixtures of herbal drugs on selected renal functions

R. Masteiková1, R. Klimas2, B. B. Samura3, A. Savickas2, B. A. Samura4, S. I. Belaij3, I. B. Samura3, M. Rabišková1, Z. Chalupová1, J. Bernatonienė2
1 Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav technologie léků
2 Kaunasská univerzita medicíny, Litva, Katedra technologie léků a sociální farmacie
3 Zaporožská státní univerzita medicíny, Ukrajina, Katedra klinické farmakologie
4 Národní univerzita medicíny, Ukrajina, Katedra farmakoterapie

The paper aimed to determine the effects of mixtures of selected medicinal plants on some physiological renal functions, i.e. excretion of urine and electrolytes and changes in the quantity of prostaglandins E2 (PGE2) and kallikrein-kinins in rat blood plasma after water and salt load. The following medicinal plants were selected for the examination: downy birch (Betula pubescens EHRH.), everlasting flower (Helichrysum arenarium L. MOENCH.), hawthorn (Crataegus oxyacantha L.), woodland strawberry (Fragaria vesca L.), sweet corn (Zea mays L.), German chamomile (Matricaria recutita L.), and field horsetail (Equisetum arvense L.). Herbal drugs were used to compose 6 mixtures. Extracts from these mixtures were administered to Wistar strain males and their effects were compared with the effects of an administered suspension of hydrochlorothiazide, an extract from field horsetail herb alone, and a control group of animals which was not administered any preparation. The greatest diuretic effect was found in a mixture composed of birch leaves (Betulae folium), hawthorn berries (Crataegi fructus), strawberry leaves (Fragariae folium), corn silk (Maydis stigmata), chamomile flowers (Matricariae flos), and horsetail herb (Equiseti herba). Its effect was greater by 47 % and 34 % than the effect of a horsetail herb extract and a hydrochlorothiazide suspension (p

Keywords: mixture of herbal drugs; renal function; diuresis; electrolytes

Received: July 10, 2006; Accepted: January 31, 2007; Published: February 1, 2007  Show citation

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Masteiková R, Klimas R, Samura BB, Savickas A, Samura BA, Belaij SI, et al.. An orientational examination of the effects of extracts from mixtures of herbal drugs on selected renal functions. Čes. slov. farm. 2007;56(2):85-89.
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    References

    1. Sibernagl, S., Despopoulos, A.: Atlas fyziologie člověka. 2. české vyd. Praha, Grada Avicenum, 1993, s. 120.
    2. Vitela, M. et al.: Am. J. Physiol. Regul. Integr. Comp. Physiol., 2005; 288, R856-862. Go to original source... Go to PubMed...
    3. Acierno, M. J., Labato, M. A.: Clin. Tech. Small Anim. Pract., 2005; 20, 23-30. Go to original source... Go to PubMed...
    4. Trojan, S. et al.: Lékařská fyziologie. Praha, Grada Avicenum, 1994, s. 257.
    5. Parfenov, V. A.: Ter. Arkh., 2005; 77, 59-59.
    6. Vetchý, D., Ceral, J.: Neurologie pro praxi, 2005; 6, 218-220.
    7. Katzung, B. G.: Základní & klinická farmakologie. 2. české vyd. Jinočany, Nakladatelství a vydavatelství H & H, 1995, s. 221.
    8. Klepser, T. B.: In: Modern Pharmaceutics, 4th ed. (Banker, G. S., Rhodes, C. T. eds.). New York and Basel, Marcel Dekker, 2002, s. 73.
    9. Raskin, I., Ripoll, C.: Curr. Pharm. Design, 2004; 10, 3419-3429. Go to original source... Go to PubMed...
    10. European Pharmacopoeia 2nd ed. Strasbourg, 1997.
    11. Berchin, E. B.: Chim. Farm. Žurn., 1977; 5, 3-11.
    12. European Pharmacopoeia 5th ed. Strasbourg, 2005.
    13. Tahara, D., Yano, I.: Aquaculture, 2001; 220, 791-800. Go to original source...
    14. Liu, J. et al.: Perfusion, 2006; 21, 179-183. Go to original source... Go to PubMed...
    15. Nekrasova, A. A. et al.: Kardiologija, 1986; 26, 13-20.
    16. Al-Awwadi, N. A. et al.: J. Agric. Food Chem., 2005; 53, 151-157. Go to original source... Go to PubMed...

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