Čes. slov. farm. 1999, 48(2):94-96
A Contribution to the Analytical Profile of N-isopropyl-3-[2-acetyl-4-(propoxycarbonyl-amino)phenoxy]-2-hydroxypropylammonium Chloride (BL 343 Ac)
- 1 Ústav chemických léčiv Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno
- 2 Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty UniverzityKomenského, Bratislava
The paper presents some procedures of the analytical evaluation of a newly prepared substance withbeta-adrenolytic activity. The substance was characterised by its melting point, solubility; theexperimental partition coefficient, dissociation constant, surface activity were determined. Theprocedures for identification, purity evaluation and determination of the content of the activeprinciple ( 1 H-NMR, 13 C-NMR, IR, UV spectra, thin-layer chromatography, acidimetric determina-tion in a non-aqueous medium, extraction titration in a heterogeneous medium, extraction-photo-metric determination) were elaborated.
Keywords: N-isopropyl-3-[2-acetyl-4-(propoxycarbonylamino)phenoxy]-2-hydroxypropyl-ammonium chloride; identification; purity detection; content determination
Published: February 1, 1999 Show citation
| ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
Blešová M, Csöllei J, Novomeský P, Opatřilová R. A Contribution to the Analytical Profile of N-isopropyl-3-[2-acetyl-4-(propoxycarbonyl-amino)phenoxy]-2-hydroxypropylammonium Chloride (BL 343 Ac). Čes. slov. farm. 1999;48(2):94-96.