JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2021, 70(4):127-135 | DOI: 10.5817/CSF2021-4-127

The role of vitamin D in primary and secondary prevention in orthopaedic patients

Michal Čečrle1,2,3,*, Norbert Didič4, Milada Halačová2,5, Dalibor Černý1,2,4
1 Farmakologický ústav, 1. lékařská fakulta Univerzity Karlovy, Praha
2 Oddělení klinické farmacie, Nemocnice Na Homolce, Praha
3 Oddělení klinické farmacie, Lékárna Nemocnice Hořovice
4 Oddělení ortopedie a traumatologie, Nemocnice Rudolfa a Stefanie, a.s., Benešov
5 Ústav farmakologie, 2. lékařská fakulta Univerzity Karlovy, Praha

The article discusses the effect of vitamin D on primary and secondary prevention of fractures and its effect on conditions after selected orthopaedic procedures. Fractures can be divided into traumatic, fatigue and pathological according to the cause. One of the complications of fracture is the formation of a nonunion. In addition to dealing with fractures, a total joint replacement is another common procedure in orthopaedic surgery. Because insufficient muscle strength can increase the risk of falls and thus result in a fracture, these topics are also mentioned in this article. Due to the impact of vitamin D deficiency on various musculoskeletal disorders, orthopaedic surgeons should pay more attention to the patient's vitamin D status and be familiar with different strategies for preventing hypovitaminosis D, although clear evidence-based medical recommendations are still insufficient.

Keywords: vitamin D; orthopaedics; fracture; total joint replacement; osteoporosis
Grants and funding:

Práce byla podpořena MZ ČR - RVO (NNH, 00024883).

Received: June 5, 2021; Accepted: July 6, 2021; Published: April 1, 2021  Show citation

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Čečrle M, Didič N, Halačová M, Černý D. The role of vitamin D in primary and secondary prevention in orthopaedic patients. Čes. slov. farm. 2021;70(4):127-135. doi: 10.5817/CSF2021-4-127.
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