JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2013, 62(4):174-176

Antioxidant activity of extracts and HPLC analysis of flavonoids from Capella bursa-pastoris (L.) Medik

Renata Kubínová1,*, Věra ©pačková1, Emil ©vajdlenka1, Katarina Lučivjanská2
1 Veterinární a farmaceutická univerzita, Farmaceutická fakulta, Ústav přírodních léčiv, Brno
2 Univerzita veterinárskeho lekárstva a farmácie, Katedra farmakognósie a botaniky

The flavonoid profile of Capsella bursa-pastoris (L.) Medik. (Brassicaceae) and the antioxidant activity of its methanolic and aqueous extracts were studied. Glycosides of quercetin, chrysoeriol, kaempferol, and isorhamnetin were identified. Chrysoeriol O-glucoside and isorhamnetin O-rutinoside were detected in this species for the first time. The extracts presented an antioxidant activity against DPPH radicals, peroxyl radicals, hydroxyl radicals, and hydrogen peroxide.

Keywords: Capsella bursa-pastoris; flavonoids; antioxidant activity

Received: June 12, 2013; Accepted: July 4, 2013; Published: April 1, 2013  Show citation

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Kubínová R, ©pačková V, ©vajdlenka E, Lučivjanská K. Antioxidant activity of extracts and HPLC analysis of flavonoids from Capella bursa-pastoris (L.) Medik. Čes. slov. farm. 2013;62(4):174-176.
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References

  1. Grosso C., Vinholes J., Silva L. R., de Pinho P. G., Gonçalves R. F., Valentão P., Jäger A. K., Andrade P. B. Chemical composition and biological screening of Capsellabursa-pastoris. Rev. Bras. Farmacogn. 2011; 21, 635-644. Go to original source...
  2. Kweon M. H., Kwak J. H., Ra K. S., Sung H. Ch., Yang H. Ch. Structural characterization of a flavonoid compounds cavenging superoxide anion radica lisolated from Capsellabursa-pastoris. J. Biochem. Mol. Biol. 1996; 29, 423-428.
  3. Griffithsa D. W., Deightona N., Bircha A. N. E., Patrianb B., Baurb R., Städler E. Identification of glucosinolates on theleafsurface of plants from the Cruciferae and other closely related species. Phytochemistry 2001; 57, 693-700. Go to original source... Go to PubMed...
  4. Jugea N., Mithena R. F., Trakaa M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell. Mol. Life Sci. 2007; 64, 1105-1127. Go to original source... Go to PubMed...
  5. Glawischnig E. Camalexin. Phytochemistry 2007; 68, 401-406. Go to original source... Go to PubMed...
  6. Onyilagha J., Bala A., Hallett R., Gruber M., Soroka J., Westcott N. Leaf flavonoids of the cruciferous species, Camelina sativa, Crambespp., Thlaspiarvense and several other genera of the family Brassicaceae. Biochem. Syst. Ecol. 2003; 31, 1309-1322. Go to original source...
  7. Blois M. S. Antioxidant determinativ by the use of a stable free radical. Nature 1958; 181, 1199-1200. Go to original source...
  8. Ritov B. R., Goldma R., Stoyanovsky A. D., Menshikova E. V., Kagan E. V. Antioxidant paradoxes of phenolic compounds: peroxyl radiál scavenger nad lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmatic reticulum Ca2+ -ATPase via thiol oxidation by its phenoxyl radical. Arch. Biochem. Biophys. 1995; 321, 140-152. Go to original source... Go to PubMed...
  9. Parejo I., Petrakis C. H., Kefalas P. J. A transition metal enhanced luminal chemiluminescence in the presence of a chelator. Pharmacol. Toxicol. Method 2000; 43, 183-190. Go to original source... Go to PubMed...
  10. Guo S., Deng Q., Xiao J., Xie B., Sun Z. Evaluation of antioxidant aktivity and preventing DNA damage effect of pomegranate extracts by chemiluminiscence method. J. Agric. Food. Chem. 2007; 55, 3134-3140. Go to original source... Go to PubMed...
  11. Cao G., Sofic E., Prior R. L. Antioxidant and prooxi dant behavior of flavonoids: structure-activity relationships. Free Radic. Biol. Med. 1997; 22, 749-760. Go to original source... Go to PubMed...




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