Životné jubileum Dr.h.c. prof. RNDr. Václava Suchého, DrSc.

Čes. slov. farm. 2016, 65(4):127  

Phenolic compounds in leaves insertions of Mentha × villosa Huds. cv. Snežná

Daniela Tekeľová, Silvia Bittner Fialová, Jaroslav Tóth, Szilvia Czigle

Čes. slov. farm. 2016, 65(4):161-165 | DOI: 10.36290/csf.2016.031  

Lamiaceae plants mostly accumulate active ingredients in their leaves. The subfamily Nepetoideae, including the genus Mentha L., is characterized by the presence of essential oil and antioxidant phenolics, chiefly hydroxycinnamic acids with predominance of rosmarinic acid, and flavonoids. Mentha × piperita and M. spicata are the most broadly used mints in both medicine and industry, while M. x villosa is less known in our country. Herbal drugs in the form of leaves are usually analysed unpartitioned, while single leaves insertions have only been studied occasionally. Therefore, the aim of this work was the quantification...

Constituents of the leaves of Cornus officinalis Sieb. et Zucc.

Vladimír Forman, Daniel Grančai, Branislav Horváth

Čes. slov. farm. 2016, 65(4):128-131 | DOI: 10.36290/csf.2016.028  

The paper deals with the isolation and identification of the constituents of Cornus officinalis Sieb. et Zucc. leaves. There was isolated β-sitosterol from petroleum ether extract, glucose and saccharose from methanolic extract and gallic acid, quercetin and quercetin-3-O-glucoside (isoquercitrin) from aqueous-methanolic extract. Isolates were identified by physico-chemical data, and by comparing with authentic samples and literature data. The compounds I - V were isolated from the leaves of Cornus officinalis Sieb. et Zucc. for the first time.

Cellular and molecular mechanisms of action of bitter compounds: recent knowledge and perspective

Milan Nagy, Pavel Mučaji

Čes. slov. farm. 2016, 65(4):132-138 | DOI: 10.36290/csf.2016.029  

This overview paper describes in its introductory part bitter-tasting herbal drugs in the context of their traditional use in the loss of appetite and digestive disorders. Then, it mentions current knowledge on signals origin in bitter taste receptors leading to different, unexpected physiological processes. Newly observed biological effects of bitter tastants are correlated with modern trends of their complex study with an aim to develop new drugs primarily acting on bitter taste receptors.

Use of plant extracts as an efficient alternative therapy of respiratory tract infections

Karel Šmejkal, Veronika Rjašková

Čes. slov. farm. 2016, 65(4):139-160 | DOI: 10.36290/csf.2016.030  

Medicinal plants are advantageously used in the treatment of respiratory tract diseases. Upper respiratory tract catarrh is one of the diseases associated with seasonal weakening of immunity, and therefore, plant drugs with a non-specific immunomodulation effect are often used. Such plants include, but are not limited to, Echinacea (Echinacea purpurea) and American ginseng (Panax quinquefolius). In combination with medicinal plants having antibacterial and antiseptic effects, such as thyme (Thymus vulgaris) and pelargonium (Pelargonium sidoides), they can constitute efficient help in the treatment of respiratory tract diseases,...

In memoriam - doc. RNDr. PhMr. Jarmila Vlčková, CSc.

J. Čižmárik

Čes. slov. farm. 2016, 65(4):166