JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2018, 67(2):66-70 | DOI: 10.36290/csf.2018.009

Selenium in the prevention and subsidiary therapy of cancer of soft tissues

Andrea Raganová1,*, Andrea Gažová1, Igor Tomo2, Viera Kristová1
1 Ústav farmakológie a klinickej farmakológie LF UK, Bratislava, SR
2 Ústav lekárskej biológie, genetiky a klinickej genetiky, LF UK Bratislava, SR

Selenium as an antioxidant has attracted attention because of its anticancer activity. This review presents a view on selenium and its compounds exerting influence against cancer in the soft tissues. The results reveal a significant strong association between a low selenium level in blood and a cancer risk. Seleno-supplementation is important in the prevention of metastatic cancer. These results help to elucidate the anticancer effect of selenium providing further evidence to exploit novel anticancer agents targeting selenium-containing organic compounds.

Keywords: selenium; cancer prevention; cancer treatment; soft tissues

Received: April 13, 2018; Accepted: May 10, 2018; Published: February 1, 2018  Show citation

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Raganová A, Gažová A, Tomo I, Kristová V. Selenium in the prevention and subsidiary therapy of cancer of soft tissues. Čes. slov. farm. 2018;67(2):66-70. doi: 10.36290/csf.2018.009.
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