JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2016, 65(2):70-77 | DOI: 10.36290/csf.2016.013

Phenolic compounds of the genus Iris plants (Iridaceae)

Olga O. Mykchailenko1,*, Vladimir M. Kovalyov2
1 National University of Pharmacy, Department of Botany, Kharkiv, Ukraine
2 National University of Pharmacy, Department of Pharmacognosy, Kharkiv, Ukraine

This article presents the results of testing of phenolic compounds (flavonoids, isoflavonoids, xanthones, phenolcarboxylic acids, tannins, coumarins, etc.) in the rhizomes of four Iris species (Iris sibirica L., Iris pseudacorus L., Iris imbricatа Lindl., Iris hungarica Waldst. et Kit.). With the use of paper and thin-layer chromatography, fifteen phenolic compounds were identified: gallic, coumaric, cinnamic, chlorogenic, neochlorogenic, ferulic, caffeic acids; kaempferol, quercetin, hispidulin, daidzein, genistein, formononetin, mangiferin and isomangiferin. Quantitative contents of flavonoids (1.2-3.7%), hydroxycinnamic acids (0.6-6.5%), γ-pyrones (0.01-0.8%), tannins (6-14%), isoflavonoids (1-2%), polyphenolic compounds (up to 3%) in the rhizomes of the Iris species were determined. Chosen plants belong to natural flora and have been often cultivated. However, this phytochemical analysis for the main groups of the biologically active substances shows a perspective use of the Iris species in medicine.

Keywords: Iris species; Iridaceae; phenolic compounds; chromatography; qualitative analysis; quantitative contents

Received: February 26, 2016; Accepted: March 9, 2016; Published: February 1, 2016  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Mykchailenko OO, Kovalyov VM. Phenolic compounds of the genus Iris plants (Iridaceae). Čes. slov. farm. 2016;65(2):70-77. doi: 10.36290/csf.2016.013.
Download citation

References

  1. Kochetkov N. K. Chemistry of biologically active natural compounds. Moscow: Chemistry 1970.
  2. Khare C. P. Indian medicinal plants. Berlin, Heidelberg: Springer-Verlag 2007; 336-337. Go to original source...
  3. Chekman J. S., Zavalko I. V. Flavonoids: pharmacological aspects. Phytotherapy J. 2008; 1, 3-11.
  4. Korulkin D. Y., Abilov D. A., Muzychkina R. A., Tolstikov G. A. Natural flavonoids. Novosibirsk: Geo 2007.
  5. Kuznetsova G. A. Natural coumarins and furokumariny. Leningrad: Nauka 1967.
  6. Kochetova M. V., Semenistaya E. N., Larionov O. G., Revina A. A. Determination of biologically active phenols and polyphenols in various objects by chromatographic techniques. Russian Chemical Reviews 2007; 76(1), 79-90. Go to original source...
  7. Zatylnikova O. A., Osolodchenko T. P., Kovalev V. N. Antimicrobial activity of extracts of Iris pseudacorus L. Scientific J. Annals of Mechnikov's Institute 2010; 4, 43-47.
  8. Kovalev V. N. (ed.) Practicum on Pharmacognosy: Textbook for students. Kharkiv: Golden Pages 2003.
  9. Goldblatt P., Manning J. C. The Iris Family: Natural History and Classification, Timber Press: Portland 2008.
  10. Dykes W. R. The Genus Iris. New York: Dover Publications 1974.
  11. Austin C. Irises: a gardeners encyclopedia; Portland: Timber Press 2005.
  12. Williams Ch. A., Harborne J. B., Colasante M. Flavonoid and xanthone patterns in bearded Iris species and the pathway of chemical evolution in the genus. Biochemical Systematics and Ecology. 1997; 25(4), 309-325. Go to original source...
  13. Plant Resources of Russia and neighboring countries: flowering plants, their chemical composition, the use of: family Butomaceae-Typhacea. St. Petersburg: Nauka 1994; 77-82.
  14. Kassak P. Secondary metabolites of the choosen genus Iris spesies. J. acta universitatis agriculturae et silviculturae mendelianae brunensis. 2012; 32(8), 269-280. Go to original source...
  15. Kukula-Koch W., Sieniawska E., Widelski J., Urjin O. Major secondary metabolites of Iris spp. Phytochemistry reviews. 2013; 12(4), 1-32. Go to original source...
  16. Rahman A. U., Nasim S., Baig I., Jalil S., Orhan I., Sener B., Choudhary M. I. Anti-inflammatory isoflavonoids from the rhizomes of Iris germanicа. J. of Ethnopharmacology. 2003; 86, 177-180. Go to original source... Go to PubMed...
  17. Wollenweber E., Stevens J. F., Klimo K., Knauft J., Frank N., Gerhäuser C. Cancer Chemopreventive in vitro activities of isoflavones from Iris germanica. Planta Med. 2003; 69, 15-20. Go to original source... Go to PubMed...
  18. Mosyakin S. L., Fedoronchuk M. M. Vascular plants of Ukraine: a nomenclatural checklist. Kiev 1999; 31-33.
  19. Czerepanov S. K. Vascular plants of Russia and adjacent states (the former USSR). Cambridge 2007; 280-282.
  20. State pharmacopoeia of the USSR. 11th ed. Vol. 1. General methods of analysis. Herbal drugs/USSR Ministry of Health. Moscow: Medicine 1987.
  21. State pharmacopoeia of the USSR. 11th ed. Vol. 2. General methods of analysis. Herbal drugs/USSR Ministry of Health. Moscow: Medicine 1990.
  22. State Pharmacopoeia of Ukraine. 1st ed. Appendix 1. Kharkiv: State Enterprise: Scientific and Expert Pharmacopoeial Centre 2004.
  23. State Pharmacopoeia of Ukraine. 1st ed. Appendix 2. Kharkiv: State Enterprise: Scientific and Expert Pharmacopoeial Centre 2008.
  24. Belikov V. V., Schreiber M. S. Methods of analysis of flavonoid compounds. Pharmacy 1970; 19(1), 68-72.
  25. Kovalyova A. I., Georgiyevskiy G. V., Kovalyov V. M., Komisarenko A. I., Tymchenko N. I. Development of new piflamin medicine standardization methods. Farmakom 2002; 2, 92-97.
  26. Aslanukov A. K., Ayrapetova A. U., Serebryanaya F. C. Identification and quantification of the amount of xanthones in terms mangiferin in the grass kopeck Caucasus (Hedysarum caucasicum Bieb.). Development, research and marketing of new pharmaceutical products. 2009; 64, 11-13.
  27. Rodionenko G. I. An outline of a new and evolutionary botanical classification of Irises. The Iris Year Book. The British Iris Society 1962; 103-119.
  28. Kovalev V. N., Mykhailenko O. A., Kovalev S. V. Coumarins from Yellow iris. Khimiya Rastitelnogo Surya 2013; 3, 201-205.




Czech and Slovak Pharmacy

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.