JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2015, 64(5):212-214

Determination of acid-base dissociation constants of newly synthesized arylethanolamine derivatives using capillary zone electrophoresis

Iva Kapustíková*, Matej Maruniak, Ľubica Havranová-Sichrovská, Lukáš Stanzel, Ivan Malík, Eva Sedlárová
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic

Grants and funding:

This work was supported by the following grants: FaF UK/63/2015; FaF UK/28/2015; FaF UK/29/2015; FaF UK/44/2015; Grant UK/346/2015; Comenius University in Bratislava Science Park supported by the Research and Development Operational Programme funded by the ERDF - Grant number: ITMS 26240220086.

Published: May 1, 2015  Show citation

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Kapustíková I, Maruniak M, Havranová-Sichrovská Ľ, Stanzel L, Malík I, Sedlárová E. Determination of acid-base dissociation constants of newly synthesized arylethanolamine derivatives using capillary zone electrophoresis. Čes. slov. farm. 2015;64(5):212-214.
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References

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  2. Babić S., Horvat A. J. M., Mutavdžić Pavlović D., Kaštelan-Macan M. Determination of pKa values of active pharmaceutical ingredients. Trends Anal. Chem. 2007; 26, 1043-1061. Go to original source...
  3. Fuguet E., Reta M., Gibert C., Rosés M., Bosch E., Ràfols C. Critical evaluation of buffering solutions for pKa determination by capillary electrophoresis. Electrophoresis 2008, 29, 2841-2851. Go to original source... Go to PubMed...
  4. Šlampová A., Křivánková L., Gebauer P., Boček P. J. Standard systems for measurement of pKa values and ionic mobilities 2. Univalent weak bases. J. Chromatogr. A 2009; 1216, 3637-3641. Go to original source... Go to PubMed...
  5. Maruniak M. Preparation, physico-chemical properties and biological activity evaluation of cardiovascularactive potential drugs from the group of phenylcarbamic acid derivatives (Arylethanolamines, Aryloxyaminopropanols). Dissertation thesis. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University in Bratislava 2012.
  6. Robinson D. Buffer calculator. http://dbr.csoft.net/chem/bufcalc.php (24. 6. 2015).




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