Čes. slov. farm. 2012, 61(4):169-171
Formulation of salvia-containing gels
- 1 Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra galenickej farmácie
- 2 Farmaceutická fakulta UK v Bratislave, Katedra farmakognózie a botaniky
The trend during the past years is to prefer natural drugs to synthetically prepared medicines. Due to its important antiphlogistic, antiseptic and antihidrotic effects, Salvia officinalis L. has a wide use in medicine, pharmacy and cosmetics in various dosage forms. The aim of this research was the formulation of Salvia officinalis L. in the form of a tincture to hydrogels. Gels were parallelly prepared on the basis of the natural polymer chitosan and the synthetic polymer Carbopol® 940. The evaluation was focused on the influence of the anionic polymer and the cationic polymer in different concentrations on hydrogel flow properties. Glycerol functioning as a humectant was used in various percentage ratios. On the basis of the determination of rheological parameters and flow curves lapses the most suitable hydrogel from the application point of view was selected.
Keywords: hydrogel; Salvia officinalis L.; chitosan; Carbopol® 940; rheological parameters
Grants and funding:
Tento výskum bol podporený grantami VEGA č. 1/0024/11 a grantom FaF UK 8/2012, 9/2012.
Received: April 20, 2012; Accepted: May 25, 2012; Published: April 1, 2012 Show citation
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