Čes. slov. farm. 2007, 56(4):178-182
Voltage gated calcium channels: structure, characteristics and terminology
- Univerzita Komenského, Farmaceutická fakulta, Katedra farmaceutickej analýzy a nukleárnej farmácie, Bratislava, Slovenská republika
Voltage-gated Ca2+ channels are the major pathway of Ca2+ entry into the cells. Their activity is essential to couple electrical signals from the cell surface to physiological events in cells. Several pharmacologically, structurally and kinetically distinct calcium channel types have been identified at the electrophysiological and molecular levels. This review aims to describe the functional, structural and pharmacological properties of voltage-gated calcium channels.
Keywords: voltage-dependent Ca2+ channels; types of calcium channel proteins; electrophysiology; terminology; subunits
Received: April 25, 2007; Accepted: June 1, 2007; Published: April 1, 2007 Show citation
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