Čes. slov. farm. 2005, 54(4):159-162
Advances in Enantioselective TLC of Therapeutic Agents
- 1 Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav chemických léčiv
- 2 Akademie věd ČR Brno, Ústav analytické chemie
Enantioselective TLC represents a still developing field of analysis of therapeutic agents. In recent years, similarly as in HPLC, mainly direct separations of enantiomers without their preceding derivatization have been published, preferentially using chiral stationary phases, separations with a chiral selector in the mobile phase being less frequent. In the future, a larger choice of commercially available chiral stationary phases could contribute to a more widespread use of enantioselective TLC.
Keywords: enantiomers; TLC; therapeutic agents
Received: September 10, 2004; Accepted: December 14, 2004; Published: April 1, 2005 Show citation
References
- Maier, N. M., Franco, P., Lindner, W.: J. Chromatogr. A, 200l; 906, 3-33.
- Stefan, R.- I., van Staden, J. F., Aboul - Enein, H. Y.: Cryst. Eng., 2001; 4, 113-118.
Go to original source...
- Gubitz, G., Schmid, M. G.: Biopharm. Drug. Dispos., 2001; 22, 291-336.
Go to original source...
Go to PubMed...
- Bereznitski, Y., Thompson, R., O'Neill, E., Grinberg, N.: J. AOAC Int., 2001; 84, 1242-1251.
- Šubert, J., Šlais, K.: Pharmazie, 2001; 56, 355-360.
- Zhu, Q., Deng, Q., Zeng, L.: Yaowu Fenxi Zazhi, 2002; 22, 155-158.
- Bhushan, R., Martens, J.: Biomed. Chromatogr., 2001; 15, 155-165.
Go to original source...
Go to PubMed...
- Gocan, S.: J. Chromatogr. Sci., 2002; 40, 538-549.
Go to original source...
Go to PubMed...
- Lepri, L., Del Bubba, M., Cincinelli, A., Boddi, L.: J. Planar. Chromatogr., 2001; 14, 134-136.
- Xu, L, He, J., Liu, L., Deng, Q. Y.: Fenxi Ceshi Xuebao, 2003; 22 (2), 1-4.
- Xu, L., Liu, L., He, J., Ma, G., Deng, Q.: Zhongshan Daxue Xuebao, Ziran Kexueban Guangzhou, 2002; 41, 115-117.
- Xu, L., He, J., Liu, L., Ma, G., Deng, Q.: Fenxi Huaxue, 2003; 31, 537-540.
Go to original source...
- Kubota, T., Yamamoto, C., Okamoto, Y.: J. Am. Chem. Soc., 2000; 122, 4056-4059.
Go to original source...
- Zhu, Q., Yu, P., Deng, Q., Zeng, L.: J. Planar Chromatogr., 2001; 14, 137-139.
Go to original source...
- Zhu, Q., Ma, G., Deng, Q., Zeng, L.: Fenxi Huaxue, 2000; 28, 349-352.
- Aboul-Enein, H. Y., El-Awady, M. I., Heard, C. M.: Pharmazie, 2002; 57, 169-171.
Go to original source...
Go to PubMed...
- Suedee, R., Srichana, T., Saelim, J., Thavonpibulbut, T.: J. Planar Chromatogr., 2001; 14, 194-198.
- Bhushan, R., Martens, J., Arora, M.: Biomed. Chromatogr., 2001; 15, 151-154.
Go to original source...
Go to PubMed...
- Bhushan, R., Arora, M.: Ibid., 2001; 15, 433-436.
- Bhushan, R., Arora, M.: Ibid., 2003; 17, 226-230.
- Aboul-Enein, H. Y., El-Awady, M., I., Heard, C. M.: Biomed. Chromatogr., 2003; 17, 325-334.
Go to original source...
Go to PubMed...
- Sajewicz, M., Pietka, R., Kowalska, I.: J. Planar Chromatogr., 2004; 17, 173-176.
Go to original source...
- Mielcarek, J.: Drug Dev. Ind. Pharm., 2001; 27, 175-179.
Go to original source...
Go to PubMed...
- Aboul-Enein, H. Y., El-Awady, M. I., Heard, C. M.: J. Liq. Chromatogr., Rel. Technol., 2000; 23, 2715-2726.
Go to original source...
- Li, G., Huang, M., Yang, G. et al.: Shandong Daxue Xuebao, Ziran Kexueban, 2001; 36, 429-432.
- Zhu, C., Zhao, J., Huang, M., Wang, M.: Shandong Daxue Xuebao, Lixueban, 2003; 86-88.
- Li, G., Huang, M., Yang, G. et al.: Sepu, 1999; 17, 215-216.
Go to original source...
Go to PubMed...
- Lepri, L., Boddi, L., Del Bubba M., Cincinelli, A.: Biomed. Chromatogr., 2001; 15, 196-201.
Go to original source...
Go to PubMed...
- Görög, S.: In: Detection - Oriented Derivatization Techniques in Liquid Chromatography, Chromatogr. Sci. Ser., Vol. 48 (Lingeman, H., Underberg, W. J. M., eds.), New York and Basel, Marcel Dekker, 1990, s. 193-216.
- LeFevre, J. W.: J. Chromatogr. A, 1993; 653, 293-302.
Go to original source...
- LeFevre, J. W.: J. Chem. Educ., 1998; 75, 1287-1290.
Go to original source...
- LeFevre, J. W., Bonzagni, N. J., Chappell, L. L. et al.: J. Labelled Compd. Radiopharm., 1998; 41, 477-489.
Go to original source...
- LeFevre, J. W., Rogers, E. D., Pico, L. L., Botting, C. L.: Chromatographia, 2000; 52, 648-652.
Go to original source...
- LeFevre, J. W., Gublo, E. J., Botting, C. et al.: J. Planar. Chromatogr., 2000; 13, 160-165.
Go to original source...
- Nagata, Y., Iida, T., Sakai, M.: J. Mol. Catal. B: Enzymatic, 2001; 12, 105-108.
Go to original source...
- Heuser, D., Meads, O.: J. Planar Chromatogr., 1993; 6, 324-325.
- Spell, J. C., Stewart, J. T.: Ibid., 1997; 10, 222-224.