JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2005, 54(2):60-64

Adsorption of Substances on Active Charcoal - Part 3: Stobadin Acylderivatives

M. Stankovičová1, Ľ. Stráska1, K. Záreczká1, Ž. Bezáková1, L. Beneš2
1 Farmaceutická fakulta Univerzity Komenského v Bratislave, Katedra farmaceutickej chémie
2 Farmaceutická fakulta Veterinární a farmaceutické univerzity Brno, Ústav chemických léčiv

The paper studies the adsorption of nine stobadin acylderivatives on active charcoal. Freundlich model of adsorption was employed to evaluate the course of adsorption in dependence on the concentration of substances. At the same time, the dependence of adsorption on lipophilicity and structural parameters of substances was evaluated. The dependence of the amount of the adsorbed substance on time served for the calculation of the rate constant of the 1st order of adsorption process. These values correlate with the parameters characterizing the size of the molecule.

Keywords: stobadin acylderivatives; stobadin; adsorption on active charcoal

Received: October 31, 2003; Accepted: December 11, 2003; Published: February 1, 2005  Show citation

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Stankovičová M, Stráska Ľ, Záreczká K, Bezáková Ž, Beneš L. Adsorption of Substances on Active Charcoal - Part 3: Stobadin Acylderivatives. Čes. slov. farm. 2005;54(2):60-64.
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