JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2003, 52(5):244-247

Granulometry and Fractal Dimension

Z. Zatloukal
Katedra farmaceutické technologie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové

The fractal character of exponential particle size distribution makes it possible to use fractaldimension for the evaluation of the results of granulometric analysis. The conditions of sedimentationanalysis of talc in aqueous solution were optimized by adding nonionogenic tenside anddeflocculation electrolyte. Dispersion analysis demonstrated the suitability of minimally 0,2 g/l ofpolysorbate 80 for talc soaking. In the evaluation of pharmaceutical granulometry, it is advisable tosupplement the usually reported specific surface area with fractal dimension, which primarilycontributes to a more general interpretation of variability of particle size.

Keywords: particle size analysis; fractal dimension; particle size distribution; talc

Published: May 1, 2003  Show citation

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Zatloukal Z. Granulometry and Fractal Dimension. Čes. slov. farm. 2003;52(5):244-247.
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