JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2000, 49(1):21-25

Human Hepatocyte II. - Cryopreservation

Z. Dvořák1, J. Adler2, J. Ulrichová1
1 Ústav lékařské chemie a biochemie Lékařské fakulty Univerzity Palackého, Olomouc
2 Tkáňová banka Univerzitní nemocnice, Brno - Bohunice

Human hepatocytes (HH) are an optimal in vitro model for the study of xenobiotics metabolism andtoxicity. However, there is still a problem of HH availability. A promising possibility for the storageof HH for later utilization is cryopreservation. Procedures and conditions used for cryopreservationof human hepatocytes and hepatocytes of other species are presented in the present paper. Comparedare some biochemical parameters characterizing viability and functionality of fresh and thawed HH.

Keywords: human hepatocyte; cryopreservation; viability; metabolism

Published: January 1, 2000  Show citation

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Dvořák Z, Adler J, Ulrichová J. Human Hepatocyte II. - Cryopreservation. Čes. slov. farm. 2000;49(1):21-25.
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