Čes. slov. farm. 2016, 65(1):15-21 | DOI: 10.36290/csf.2016.003

Oral films as perspective dosage form

Veronika Walicová, Jan Gajdziok^*

Ústav technologie léků, Farmaceutická fakulta, Veterinární a farmaceutická univerzita v Brně, Brno, Česká republika

Oral films, namely buccal mucoadhesive films and orodispersible films represent innovative formulations for administration of a wide range of drugs. Oral films show many advantageous properties and are intended for systemic drug delivery or for local treatment of the oral mucosa. In both cases, the film represents a thin layer, which could be intended to adhere to the oral mucosa by means of mucoadhesion; or to rapid dissolution and subsequent swallowing without the need of liquid intake, in the case of orodispersible films. Main constitutive excipients are film-forming polymers, which must in the case of mucoadhesive forms remain on the mucosa within the required time interval. Oral films are currently available on the pharmaceutical market and could compete with conventional oral dosage forms in the future.

Keywords: oral cavity; oral films; buccal mucoadhesive films; orodispersible films; film-forming polymers

Received: January 13, 2016; Accepted: February 2, 2016; Published: January 1, 2016  Show citation