Czech and Slovak Pharmacy, 2023 (vol. 72), issue 1
Original Articles
New trends in advanced parkinson disease stage therapy
Mária Kolesárová, Ondrej Franko, Dalibor Kolesár, Andrea Gažová, Ján Kyselovič
Čes. slov. farm. 2023, 72(1):37-44 | DOI: 10.5817/CSF2023-1-37 
The aim of the study was to point out the contribution of new invasive therapeutic procedures in the treatment of advanced stages of Parkinson's disease (PD) in comparison with classical oral pharmacotherapy. Data originated from a group of 43 patients with PD, 39% (17) with classic treatment, 23% (10) with intestinal gel of methyl ester levodopa (Duodopa), 19% (8) of patients were using subcutaneous delivery of apomorphine (APO) and the same quantity of patients had undergone deep brain stimulation (DBS). Majority of patients had advanced stages of PD, stage 4, by standards of Hoehn and Yahr scale (Hoehn and Yahr, 1967). Research observed improvement...
Are some COVID-19 vaccines better than others regarding the short-term side effects?
Radhwan Al-Zidan, Omeed Darweesh, Muhanad Salah, Pshtiwan Bebane, Hemn Ahmed, Ghayth Abdulrazzaq, Sadeel Shanshal, Nohad AlOmari
Čes. slov. farm. 2023, 72(1):45-54 | DOI: 10.5817/CSF2023-1-45
Controlling the pandemic is primarily achieved through vaccination against COVID-19. Although various COVID-19 vaccines are used worldwide, little is known about their safety and side effects. As a result, the objectives of this research are to identify the shortterm side effects of the different COVID-19 vaccines used in Iraq. Furthermore, exploring the association between experienced side effects and the brand of vaccine received. The current study evaluated the shortterm side effects of Pfizer, Sinopharm and AstraZeneca vaccines among healthcare workers in Iraq. The study used a questionnaire that consisted of dedicated sections to collect demographic...
Review articles
Contribution to the concept of polypharmacy II. Prescription and use of medicines
Jozef Kolář, Tünde Ambrus, Dominik Grega, Lenka Smejkalová
Čes. slov. farm. 2023, 72(1):3-10 | DOI: 10.5817/CSF2023-1-3
The study defines the basic terminological structure associated with the concepts of prescribing and medication use in relation to polypharmacy. Correctly naming the current prescription or use of a medication by a particular patient allows for the selection of an appropriate change to minimize the medication burden. The aim remains to maintain the desired therapeutic outcomes with an improved quality of life.
Entry and competition of retail pharmacies: A case study of OTC drugs sales and ownership deregulation
Matúš Bilka, António Portugal Duarte, Martin Lábaj
Čes. slov. farm. 2023, 72(1):11-20 | DOI: 10.5817/CSF2023-1-11
This study provides new empirical evidence on the changes in competition and entry decisions of pharmacies after regulatory changes. It investigates the development of the retail pharmacy market in Portugal, which underwent major regulatory changes in 2004 and 2007. Sale of OTC drugs and ownership of pharmacies were liberalized while entry restrictions related to market size and the location of new pharmacies prevailed.Our empirical strategy was based on entry models and provided indirect information on the toughness of competition and entry decisions of firms in the market. We estimated and compared the entry thresholds and their ratios before...
Childhood obesity: causes, consequences, and prevention
Aus Tariq Ali, Faisal Al-Ani, Osamah Al-Ani
Čes. slov. farm. 2023, 72(1):21-36 | DOI: 10.5817/CSF2023-1-21
As a result of the dramatic increase in the prevalence of overweight and obesity among children, childhood obesity is one of the most critical global public health challenges of the 21st century. Weight gain occurs when energy intake exceeds energy expenditure. Both genetic and environmental factors (such as a sedentary lifestyle) are implicated in its pathogenesis. Childhood obesity is associated with physical, psychological, and social consequences. Obese children are at higher risk of elevated fasting blood glucose, insulin resistance, impaired glucose tolerance, type 2 diabetes, hypertension, polycystic ovarian syndrome (PCOS), atherosclerosis...