Czech and Slovak Pharmacy, 2022 (vol. 71), issue 1
Original Articles
Surviving of production probiotic strains in a selected application form
Adriána Fečkaninová, Jana Koščová, Aleš Franc, Dagmar Mudroňová, Peter Popelka
Čes. slov. farm. 2022, 71(1):27-33 | DOI: 10.5817/CSF2022-1-27 
Research in probiotics for aquaculture is at an early stage of development and much work is still needed. Lactiplantibacilli belong to the microorganisms most frequently used to prepare the probiotics. The available information is inconclusive, since few experiments with sufficiently robust design have been conducted to permit critical evaluation. The development of probiotics applicable to commercial use in aquaculture is a multistep and multidisciplinary process requiring both empirical and fundamental research, full-scale trials, and an economic assessment of its use. The aim of the study was to prepare a probiotic aquafeed via excipients and subsequently...
Cerebroprotective properties of recombinant interleukin-1 receptor - an experimental study
Katherine Shchokina, Vira Ulanova, Svitlana Drogovoz
Čes. slov. farm. 2022, 71(1):34-40 | DOI: 10.5817/CSF2022-1-34
Optimization of therapy of cerebrovascular disorders (CVD) is one of the most critical health problems. The current treatment regimen of CVD turns out to be often insufficient. Search for new drugs with cerebroprotective and antihypoxic properties is an essential task of modern medicine and pharmacy. Attention to cytokine mechanisms of ischemic brain damage in clinics and experimental research has been increased recently. Interleukin-1 (IL-1) receptor blockade is a perspective way of cerebroprotection that requires a more profound study of its mechanisms. The article contains the results of a study of cerebroprotective and antihypoxic properties of...
Review articles
Ethical and legal requirements for vaccination against COVID-19
Aleš Franc, Vladimír Bíba
Čes. slov. farm. 2022, 71(1):3-12 | DOI: 10.5817/CSF2022-1-3
In the current context, there is an extraordinary interest of states in vaccinating the population to prevent Covid-19. In the Czech Republic, gene mRNA and vector DNA vaccines are approved only with conditional marketing authorization, for which a complete and long-term safety assessment is currently lacking. Vaccines show some potential risks, such as penetration of lipid nanoparticles into surrounding tissues, incorporation of DNA into the host genome, ADE syndrome, development of resistant mutations, myocarditis, pericarditis, and thromboembolic events. Since the level of antibodies after vaccination is soon decreasing, immunity after the disease...
The role of individuals receiving health care - terminological notes
Jozef Kolář, Tünde Ambrus
Čes. slov. farm. 2022, 71(1):13-19 | DOI: 10.5817/CSF2022-1-13
The overview study characterizes the roles of individuals receiving health care: healthy person, patient, client, health care recipient/user, consumer/customer, and insured person. It outlines the rights and obligations of the recipients of care.
Colour and antioxidant activity of honey
Jan Šubert, Jozef Kolář, Jozef Čižmárik
Čes. slov. farm. 2022, 71(1):20-26 | DOI: 10.5817/CSF2022-1-20
The paper highlights the relationships between the results of instrumental colour measurement and the results of the determination of the antioxidant activity of honey (especially by DPPH and FRAP). The sufficiently close correlations show that once verified, supplemented by regression analysis and calibration, they may find application in the rapid determination of the antioxidant activity of honey.