Mobile applications as good intervention tools for individuals with depression

Petra Marešová, Blanka Klímová, Kamil Kuča

Čes. slov. farm. 2017, 66(2):55-61 | DOI: 10.36290/csf.2017.007  

At present mental disorders affect approximately 450 million people around the world. Depressive disorder is probably one of the most serious disorders and as a type of chronic disease, it represents a global threat and burdens economic and social systems of both individuals and governments worldwide. One of these most recent non-pharmacological approaches is also the so-called mHealth (mobile health), the use of mobile devices for the practice of medicine and public health, which proves to be effective particularly in the early stages of depression.The purpose of this article is to explore the most recent randomized controlled trial studies which...

Separation of phenylalanine and methionine enantiomers by HPLC method: a comparison of stationary phase types

Katarína Hroboňová, Anna Lomenova, Jozef Čižmárik, Jozef Lehotay

Čes. slov. farm. 2017, 66(2):62-66 | DOI: 10.36290/csf.2017.008  

The paper deals with enantioselective separation of amino acids by the high performance liquid chromatography method. Separations of enantiomeric forms were tested on the chiral stationary phases based on β-cyclodextrine, isopropyl carbamate cyclofructan 6, and the macrocyclic antibiotic teicoplanin. The best enantioseparation was obtained on the teicoplanin-based chiral stationary phase in the reversed-phase mode. UV spectrophotometric detection at 210 nm was used for detection of amino acids. The method was validated with respect to linearity, precision, limit of detection, limit of quantitation, and recovery. Limits of quantitation for phenylalanine...

Identifying the interprofessional agreement between community pharmacist's and general practitioner's views on collaborative practice in Slovakia

Ladislav Dubán, Tomáš Fazekaš, Magdaléna Fulmeková, Miroslava Snopková, Anna Oleárová, Magdaléna Kuželová

Čes. slov. farm. 2017, 66(2):67-75 | DOI: 10.36290/csf.2017.009  

Background: The collaboration of community pharmacists (CPs) and general practitioners (GPs) has a positive effect on healthcare outcomes. There are still many countries, where no efforts have been made to enhance this type of teamwork. There is no evidence of how GPs and CPs collaborate in Slovakia. The objective of this study is to identify the current level of GPs and CPs teamwork in Slovakia and to identify the key factors, where these professions agree. Methods: Two parallel electronic surveys were prepared and sent out by e-mail to CPs and GPs in Slovakia. The questions in the multi-choice questionnaires were divided into 6...

Targeted drug delivery system: potential application to resveratrol

Hassan Farghali, Ludmila Kameníková

Čes. slov. farm. 2017, 66(2):76-82 | DOI: 10.36290/csf.2017.010  

Drug delivery system (DDS) is intended to increasing effectiveness of drugs through targeted distribution and to reducing of unwanted effects. In this mini-review, the basic principles of nanotechnology that were developed for DDS were reported including sections on the present research in key areas that are important for future investigations. Attention is paid on resveratrol as a model phytochemical with interesting pharmacologic profile which was demonstrated in great numbers of studies and for its wide use as supplemental therapy. Due to complicated pharmacokinetic profile of resveratrol that is characterized by very low bioavailability in spite...

The image of a good pharmacist in the works of Saladin di Ascoli and Valerius Cordus

Anton Bartunek, František Šimon

Čes. slov. farm. 2017, 66(2):83-87 | DOI: 10.36290/csf.2017.011  

Separation of pharmacy from medicine induced the requirements formulation for an ideal pharmacist. Two prominent authors did so, Saladin di Ascoli (the first half of the XVth century) in the work Compendium aromatariorum (1488) and Valerius Cordus (1515-1544) in the work Dispensatorium pharmacopolarum (1546). Both of them formulate similar postulates of both professional and ethical nature, namely a knowledge of Latin, good education, experience, good character traits, need of satisfied marriage; both say that the pharmacist is required to be a good Christian, they condemn alcohol, relationships with women, poisons and abortifacients,...

Nové knihy

J. Čižmárik

Čes. slov. farm. 2017, 66(2):90  

Alois Borovanský - 95-ročný

Jozef Čižmárik

Čes. slov. farm. 2017, 66(2):88  

Vzpomínka na doc. RNDr. PhMr. Věru Spurnou, DrSc.

Lubomír Opletal

Čes. slov. farm. 2017, 66(2):89