Czech and Slovak Pharmacy, 2006 (vol. 55), issue 6
Original Articles
Measurement of Adhesive Properties of Polymers in vitro
E. Šnejdrová, M. Dittrich
Čes. slov. farm. 2006, 55(6):262-266 
Adhesive force of branched oligoesters under the in vitro conditions was studied by measuring the maximal force necessary to separate the tested sample from the base (Fmax) under different testing conditions. Branched oligoesters were synthesized from lactic and glycolic acids in the molar ratio 1:1, and from mannitol or dipentaery thritol as the branching components in concentrations of 3%, 5% or 8%. To decrease viscosity and thus to facilitate the workability and administration, triethyl citrate (TEC) in a concentration of 30% was employed. Polymeric systems for adhesive force measurements were prepared by melting oligoesters in a micro...
Liquid Ginger Extract: Technology of Production and Quality Evaluation
R. Masteiková, R. Bernatonienė, A. Savickas, Z. Chalupová, J. Bernatonienė
Čes. slov. farm. 2006, 55(6):268-271
The paper aimed to elaborate the technology of the production of a liquid ginger extract and to select and verify the methods of quality evaluation of the final preparation. The experiment revealed 70% ethanol as a suitable extraction agent. The optimal conditions for the development of an extract of good quality are established when the herbal drug is crushed to form particles passing through a sieve with a mesh size of 4000 μm, the extraction method is repercolation with the division of the charge of the drug in the relation 5:3:2, and the liquid flows from the percolator at a rate of 0.2ml/min/100 g of the drug. The presence of amino acids, saccharides,...
Potentiometric Determination of Aqueous Dissociation Constants of 2-,3-,4-{3-(4-Benzhydryl-piperazine-1-yl)-2-hydroxy-propoxy}-phenylcarbamic Acid Alkylesters, Water Insoluble Potential Blockers of ß-Adrenergic Receptors
A. Lišková, M. Blešová
Čes. slov. farm. 2006, 55(6):272-277
Apparent ionization constants (w spKa) of potential drugs, a series of twelve protonated bases, 2-,3-,4-{3-(4-benzhydryl-piperazine-1-yl)-2-hydroxy-propoxy}-phenylcarbamic acid alkylesters dihydrochlorides, were determined by automated potentiometric titrations in mixtures water - methanol. Aqueous pKa were assessed by means of Yasuda-Shedlovsky equation. Approach for pKa determination was evaluated using trimecaine hydrochloride as the model compound. The first values of ionization constants ranged approximately from 2.7 to 3.2, the second ones from 6.5 to 7.2. Only a slight decrease in ionization...
Continuous Education of Pharmacists in the Czech Republic 2nd Cycle 2002-2005
J. Kolář, J. Nováková
Čes. slov. farm. 2006, 55(6):278-285
The paper deals with continuous education of pharmacists in the Czech Republic in 2002-2005 (2nd cycle). It surveys the seminars organized within the framework of continuous education, their number, topics, and lecturers. A total number of 232 professional seminars took place, which included 339 lectures, mainly on pharmacology (76.1 %).
Review articles
University Courses in Pharmacy in the Czech Republic
J. Kolář
Čes. slov. farm. 2006, 55(6):256-261
The paper analyzes and compares the interest of applicants for the admission to the university courses in Pharmacy in the Czech Republic from the viewpoint of their number, sex, and other indices. It also characterizes the courses and discusses the requirements for pharmacists (dispensing chemists) and their possible professional careers.