JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2023, 72(1):45-54 | DOI: 10.5817/CSF2023-1-45

Are some COVID-19 vaccines better than others regarding the short-term side effects?

Radhwan Al-Zidan1, Omeed Darweesh ORCID...2,3,*, Muhanad Salah4,5, Pshtiwan Bebane6, Hemn Ahmed7, Ghayth Abdulrazzaq1, Sadeel Shanshal1, Nohad AlOmari8,*
1 College of Pharmacy, University of Mosul, Iraq
2 College of Pharmacy, Al-Kitab University, Kirkuk, Iraq
3 Department of Molecular and Cell Biology, University of Leicester, UK
4 College of Pharmacy, Hawler Medical University, Erbil, Iraq
5 Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmacy, Tishk International University, Erbil, Iraq
6 College of Education, Charmo University, Chamchamal, Iraq
7 Department of Pharmacy, Kirkuk Health Directorate, Ministry of Health, Kirkuk, Iraq
8 Pharmacy Department, AlNoor University College, Mosul, Nineveh, Iraq

Controlling the pandemic is primarily achieved through vaccination against COVID-19. Although various COVID-19 vaccines are used worldwide, little is known about their safety and side effects. As a result, the objectives of this research are to identify the shortterm side effects of the different COVID-19 vaccines used in Iraq. Furthermore, exploring the association between experienced side effects and the brand of vaccine received. The current study evaluated the shortterm side effects of Pfizer, Sinopharm and AstraZeneca vaccines among healthcare workers in Iraq. The study used a questionnaire that consisted of dedicated sections to collect demographic data, the brand of COVID-19 vaccine received, the short-term side effects, and the willingness to receive a third booster dose. Regarding the post-vaccination side effects, the studied COVID-19 vaccines showed a comparable range of side effects, such as headaches, fever, muscle pain, joint pain, malaise, tenderness, redness, as well as pain at the site of vaccination. However, the Pfizer vaccine showed a higher incidence of pain and tenderness at the site of injection and fever compared to AstraZeneca and Sinopharm, respectively. On the other hand, the Sinopharm vaccine was associated with a higher occurrence of headaches, muscle pain, joint pain, and malaise in comparison to the Pfizer and AstraZeneca vaccines, respectively. In summary, the short-term side effects of the three vaccines were comparable; however, the AstraZeneca vaccine was associated with a lower risk of side effects.

Keywords: COVID-19; vaccine; side effect; Pfizer; Sinopharm; AstraZeneca; Sputnik V

Received: November 20, 2022; Accepted: January 7, 2023; Published: January 1, 2023  Show citation

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Al-Zidan R, Darweesh O, Salah M, Bebane P, Ahmed H, Abdulrazzaq G, et al.. Are some COVID-19 vaccines better than others regarding the short-term side effects? Čes. slov. farm. 2023;72(1):45-54. doi: 10.5817/CSF2023-1-45.
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