JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2012, 61(6):276-281

Analysis of pharmaceutical care in dispensing of over-the-counter orlistat

Katarína Dobrucká, Josef Malý*, Jiří Vlček
Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové, Katedra sociální a klinické farmacie, Hradec Králové

Obesity is a chronic disease characterized by its high prevalence. Easy availability of pharmaceutical care allows pharmacies to be the first place of capture or intervention for patients who are overweight or obese. The aim of the study was to analyse the role of pharmacists and pharmacy technicians in securing the safety of self-medication with orlistat. In this prospective observational study, the patients were the people who came to the IKEM Hospital Pharmacy for self-medication with orlistat over a period of May through December 2009. The data were collected by trained pharmacists and pharmacy technicians in interviews with patients when dispensing over-the-counter (OTC) orlistat. The interview was designed by fixed questions. The results were analysed using frequency analysis, GLMz and the chi-square test with the level of significance of p < 0.05. A total of 50 patients participated in the study (44 women, median age 53 years, 41 patients with body mass index > 28). 58% patients were fully indicated for self-medication with orlistat. Self-medication with orlistat was recommended to 48% patients and was refused to 22% patients because of contraindications. 24% patients had at least one interaction with orlistat and chronic drugs. Health problems were the most common motivation for weight reduction. The data obtained in this study demonstrate an important role of pharmacists and pharmacy technicians in the assessment of suitability of self-medication with OTC orlistat and safe weight reduction within self-medication.

Keywords: obesity; pharmaceutical care; orlistat; self-medication
Grants and funding:

Práce byla podpořena grantem Univerzity Karlovy v Praze (SVV 265 005).

Received: November 7, 2012; Accepted: November 28, 2012; Published: June 1, 2012  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Dobrucká K, Malý J, Vlček J. Analysis of pharmaceutical care in dispensing of over-the-counter orlistat. Čes. slov. farm. 2012;61(6):276-281.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Armstrong M. J., Mottershead T. A., Ronksley P. E., Sigal R. J., Campbell T. S., Hemmelgarn B. R. Motivational interviewing to improve weight loss in overweight and/or obese patients: a systematic review and meta-analysis of randomized controlled trials. Obes. Rev. 2011; 12, 709-723. Go to original source... Go to PubMed...
    2. Matoulek M., Svačina Š., Lajka J. Výskyt obezity a jejích komplikací v České republice. Vnitř. Lék. 2010; 56, 1019-1027.
    3. Berenguer B., La Casa C., de la Matta M. J., Martín-Calero M. J. Pharmaceutical care: past, present and future. Curr. Pharmaceut. Des. 2004; 10, 3931-3946. Go to original source... Go to PubMed...
    4. Kolář J., Macešková B. Současné přístupy k farmakoterapii - farmaceutická péče nebo management léků? Čes. slov. farm. 2010; 59, 7-10.
    5. Vlček J., Malý J., Doseděl M. Farmaceutická péče u pacienta s diabetes mellitus a vztah ke klinické farmacii. Vnitř. Lék. 2009; 55, 384-388.
    6. Doseděl M., Malý J., Rudolf K. OTC léčiva a samoléčení průjmu a zácpy. Interní Med. 2011; 13, 127-133.
    7. Caveney E., Caveney B. J., Somaratne R. Turner J. R., Gourgiotis L. Pharmaceutical interventions for obesity: a public health perspective. Diabetes Obes. Metab. 2011; 13, 490-497. Go to original source... Go to PubMed...
    8. Mikro-verze AISLP, verze 2010.4 pro MS Windows.
    9. Anderson J. W. Orlistat for the management of overweight individuals and obesity: a review if potential for the 60 mg, over-the-counter dosage. Exp. Opin. Pharmacother. 2007; 8, 1733-1742. Go to original source... Go to PubMed...
    10. International Diabetic Federation: The IDF consensus worldwide definition of the metabolic syndrome. http://www.idf.org/webdata/docs/MetSyndrome_FINAL.pdf (22. 10. 2012).
    11. Prevost R. R. Pharmacy review: Lifestyle management of obesity: consideration for pharmacists. Am. J. Lifestyle Med. 2007; 1, 451-453. Go to original source...
    12. Zadák Z. Výživa v intenzivní péči. 2. vydání. Praha: Grada Publishing 2008; 544s.
    13. FIP Statement of Policy the role of the pharmacist in the prevention and treatment of chronic disease. Approved by FIP Council in Brazil in August 2006. http://www.fip.org/www/uploads/database_file.php?id=274&table_id= (25. 9. 2012)
    14. Hauptman J., Lucas Ch., Boldrin M. N., Collins H., Segal K. R. Orlistat in the long-term treatment of obesity in primary care settings. Arch. Fam. Med. 2000; 9, 160-167. Go to original source... Go to PubMed...
    15. Le Beller C., Bezie Y., Chabatte C., Guillemain R., Amrein C., Billaud E. M. Co-administration of orlistat and cyclosporine in a heart transplant recipient. Transplantation 2000; 70, 1541-1542. Go to original source... Go to PubMed...
    16. Nägele H., Petersen B., Bonacker U., Rödiger W. Effect of orlistat on blood cyclosporine concentration in an obese transplant patients. Eur. J. Clin. Pharmacol. 1999; 55, 667-669. Go to original source... Go to PubMed...
    17. MacWalter R. S., Fraser H. W., Armstrong K. M. Orlistat enhances warfarin effect. Ann. Pharmacother. 2003; 37, 510-512. Go to original source... Go to PubMed...
    18. Ahrens R. A., Hower M., Best A. M. Effects of weight reduction interventions by community pharmacists. J. Am. Pharm. Assoc. 2003; 43, 583-589. Go to original source... Go to PubMed...
    19. Webb M. Weight management interventions by community pharmacists: a rapid review of the evidence. National Public Health Service for Wales, 2009. http://www2.nphs.wales.nhs.uk:8080/pharmaceuticalphtdocs.nsf/Main%20Frameset?OpenFrameSet&Frame=Right&Src=%2Fpharmaceuticalphtdocs.nsf%2F1f8687d8da97650980256fa30051b0be%2Fd694bf1fb94bddbc8025756e004068f1%3FOpenDocument%26AutoFramed (1. 10. 2012).
    20. Mikušová K., Kavalírová L., Tlučhořová D., Sovišová P. OTC orlistat - role lékárny v péči o kontrolu tělesné hmotnosti. In: Doporučené postupy České lékárnické komory pro konzultační činnost v lékárnách. Olomouc: Solen, 2010; 121-132.

    Return to the content


    Czech and Slovak Pharmacy

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.