JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2011, 60(2):65-72

Bacteriocins produced by lactic acid bacteria

Andrea Bilková*, Hana Kiňová Sepová, František Bilka, Andrea Balažová
Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra bunkovej a molekulárnej biológie liečiv

Lactic acid bacteria comprise several genera of gram-positive bacteria that are known for the production of structurally different antimicrobial substances. Among them, bacteriocins are nowadays in the centre of scientific interest. Bacteriocins, proteinaceous antimicrobial substances, are produced ribosomally and have usually a narrow spectrum of bacterial growth inhibition. According to their structure and the target of their activity, they are divided into four classes, although there are some suggestions for a renewed classification. The most interesting and usable class are lantibiotics. They comprise the most widely commercially used and well examined bacteriocin, nisin. The non-pathogenic character of lactic acid bacteria is advantageous for using their bacteriocins in food preservation as well as in feed supplements or in veterinary medicine.

Keywords: lactic acid bacteria; probiotics; bacteriocins; lantibiotics; nisin; biopreservation

Received: January 27, 2011; Accepted: February 2, 2011; Published: February 1, 2011  Show citation

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Bilková A, Kiňová Sepová H, Bilka F, Balažová A. Bacteriocins produced by lactic acid bacteria. Čes. slov. farm. 2011;60(2):65-72.
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