JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2010, 59(6):256-262

The use of authorized medicinal products for human use in veterinary practice in the Czech Republic

B. Macešková, L. Smejkalová*, P. Brauner, J. Frenzelová
Veterinary and Pharmaceutical University Brno

The aim of this study was to evaluate the patterns in using authorized medicinal products for human use (HMPs) in treating animals. An analysis of the HMPs for oral administration prescribed both at the veterinary surgeries at the University of Veterinary and Pharmaceutical Sciences Brno (VFU) as well as outside the university (rural) was accomplished. Questionnaires (11 small animal practice surgeons) were processed and an analysis of the data on the human medicines dispensed at the pharmacy at VFU (2006-2007; veterinary prescriptions written in the university settings) was performed. The presence of dosage instructions in the Czech Pharmacopoeia, the pharmacotherapeutic group and the presence of equivalents among the VMPs (authorized veterinary medicinal product) were taken into consideration. The prescriptions at the surgeries at VFU comprised: 243 human HMPs (202 kinds) containing 168 different active substances involved in 47 pharmacotherapeutic groups. The recommended therapeutic dosage is stated in the Czech Pharmacopoeia for 127 substances. Thirty three of the HMP kinds (16%) could be replaced by the analogical VMPs. The small animal practice surgeons use only 152 HMPs, i.e. 112 kinds (55% of the HMP kinds used in VFU surgeries), which represents 106 active substances (63% of the scope prescribed in VFU surgeries) and 34 (72%) pharmacotherapeutic groups. For 56% of the 106 prescribed substances, no dosage is stated in the Czech Pharmacopoeia. Twenty four of the HMP kinds (21%) could be replaced by analogical VMPs. The prescription originated from order forms (VFU) shows the criteria of rational pharmacotherapy (mostly for one active substance - one HMP kind) and of the adherence to the law ("therapeutic cascades"). This study indicates that there exist different patterns in using HMP in veterinary practice among veterinary surgeons working at the University and in the small animal practice settings.

Keywords: veterinary surgeon; pharmacist; medicinal product for human use; veterinary medicinal product; dosage

Received: November 18, 2010; Accepted: October 15, 2010; Published: June 1, 2010  Show citation

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Macešková B, Smejkalová L, Brauner P, Frenzelová J. The use of authorized medicinal products for human use in veterinary practice in the Czech Republic. Čes. slov. farm. 2010;59(6):256-262.
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    References

    1. Snirc, J., Sokol, J., Seginko, J., Hera, A.: Clinical veterinary pharmacology. Martin: Neografia 2007.
    2. Directive 2001/82 EC (as amended by Directive 2004/28 EC and in the wording of the latest amendments. http://www.uskvbl.cz/id_menu = 144 (18. 3. 2008).
    3. Act No 378/2007 Code of Law (CR).
    4. Act No 166//1999 Code of Law (CR).
    5. Reg. No 54/2008 Code of Law (CR).
    6. Kernan, F.: Veterinarian and Pharmacist - yesterday, today and tomorrow. Can. Vet. J., 1997; 18, 265 - 273.
    7. Medicines, Ethics and Practice: A Guide for Pharmacists and Pharmacy Technicians. Section 1.8: Medicines for veterinary use. Section 1.9: Alphabetical list of medicines for veterinary use. http://www.rspgb.org.uk (18. 3. 2008).
    8. Lust, E.: Compounding for Animal Patients: Contemporary Issues. J. Am. Pharm. Assoc., 2004; 44, 375-386. Go to original source... Go to PubMed...
    9. Reg No 344/ 2008 Code of Law (CR).
    10. Czech Pharmacopoeia 2005. 1st ed. Praha: Grada Publishing 2005.
    11. Czech Pharmacopoeia 2005, Addendum 2006, part II. 1st ed. Praha: Grada Publishing 2006.
    12. Czech Pharmacopoeia 2005, Addendum 2007 1st ed. Praha: Grada Publishing 2007.
    13. Czech Pharmacopoeia 2005, Addendum 2008 In: Vestnik SÚKL 2008; 7, 22.
    14. European Pharmacopoeia (Ph. Eur. 6.0. http://www. edqm.eu (18. 3.2008).
    15. US Pharmacopeia. www.usp.org (18. 3. 2008).
    16. VETBASE 4 http://www.petalk.com (10. 9. 2007).
    17. Papich, M.: Saunders Handbook of Veterinary Drugs. 2nd ed. Edinburgh: Elsevier Saunders 2007.
    18. VPR V2.6. http://www.vproline.com (11. 9. 2007).
    19. Lust, E.: Veterinary Information for Pharmacists. US Pharmacist., 2004; 29, 16-23 www.uspharmacist.com. (18. 3. 2008).
    20. Czechoslovak Pharmacopoeia 1st ed. Praha: State Printing - office 1947.
    21. Czechoslovak Pharmacopoeia 1st ed. Addendum. Praha: Health Care - Publishing 1952.
    22. Czechoslovak Pharmacopoeia 2nd ed. Praha: Health care - Publishing 1954.
    23. Czechoslovak Pharmacopoeia 2nd ed. Addendum. Praha: Health care - Publishing 1959.
    24. Czechoslovak Pharmacopoeia 3rd ed. part I. Praha: AVICENUM 1970.
    25. Czechoslovak Pharmacopoeia 3rd ed. Addendum. Praha: AVICENUM 1976.
    26. Czechoslovak Pharmacopoeia 4th ed. part I. Praha: AVICENUM 1987.
    27. Czechoslovak Pharmacopoeia 4th ed. Addendum. Praha: AVICENUM 1991.
    28. Czech Pharmacopoeia 1997 part I. 1st ed. Praha: Grada Publishing 1997.
    29. Czech Pharmacopoeia 1997, Addendum 1999 part I. 1st ed. Praha: Grada Publishing 1999.
    30. Czech Pharmacopoeia 2002. 1st ed. Praha: Grada Publishing 2002 (electronic version).
    31. Czech Pharmacopoeia 2002, Addendum 2003. 1st ed. Praha: Grada Publishing 2003 (electronic version).
    32. Czech Pharmacopoeia 2002, Addendum 2004. 1st ed. Praha: Grada Publishing 2004 (electronic version).
    33. Czech Pharmacopoeia 2009. 1st ed. Praha: Grada Publishing 2009.
    34. Automated System of Medicinal Products (ASMP), publication 2008.4
    35. Authorized Veterinary Medicinal Products 2007. Prion: Hradec Králove 2007.

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