Čes. slov. farm. 2008, 57(2):58-62
Interaction of 1,4-dihydropyridines with ion channels
- Univerzita Komenského, Farmaceutická fakulta, Katedra farmaceutickej analýzy a nukleárnej farmácie, Bratislava
The pharmacology of dihydropyridines in the cardiovascular system is widely known and the effects on L-type channels are well researched. There is far less information about the action of dihydropyridines on other classes of voltage-gated calcium channels. This article aims to bring more information about dihydropyridine derivates action on voltage-gated calcium channels or on Na+ a K+channels.
Keywords: Ca2+ channels; N-channel blockers; T-channel blockers; 1,4-dihydropyridines
Grants and funding:
Práca bola realizovaná v rámci grantových projektov 1/4298/07 a 1/4299/07 VEGA Ministerstva školstva SR a grantu UK 45/2007.
Received: December 3, 2007; Accepted: January 14, 2008; Published: February 1, 2008 Show citation
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