JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2007, 56(6):264-268

Physiology and pharmacology of hyaluronic acid

E. Svanovský1,2
1 Contipro C, a. s., Dolní Dobrouč
2 Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové, katedra farmakologie a toxikologie

Hyaluronic acid represents one of the main components of the extracellular matrices. Its physical-chemical and biological properties offer a wide spectrum of use of this molecule, both in industry and medical sciences. The review paper presents our contemporary knowledge gained in the research of hyaluronic acid, describing its principal behaviour in physiological and pathological processes as well as its principal pharmacokinetic and pharmacodynamic properties.

Keywords: hyaluronic acid; biodistribution; pharmacokinetics; wound healing

Received: October 9, 2007; Accepted: October 30, 2007; Published: June 1, 2007  Show citation

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Svanovský E. Physiology and pharmacology of hyaluronic acid. Čes. slov. farm. 2007;56(6):264-268.
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    References

    1. Esposito, E., Menegatti, E.: Int, J. Pharm., 2005; 288, 35-49. Go to original source... Go to PubMed...
    2. Andre, P.: Semin. Cutan. Med. Surg., 2004; 23, 218-222. Go to original source... Go to PubMed...
    3. Seth, S. L., Brigham, B. R., Winston, J. W.: J. Bone Joint Surg. AM., 2003; 85, 1197-1204.
    4. Roux, C., Fontas, E., Breuil, V.: John Bone Spine, 2007; 74, 368-372. Go to original source... Go to PubMed...
    5. Qvistgaard, E., Chrstensen, R., Torp-Pedersen, S.: Osteoarthr. Cartilage, 2006; 14, 163-170. Go to original source... Go to PubMed...
    6. Fuchs, S., Monikes, R., Wohlmeiner, A.: Osteoarthr. Cartilage, 2006; 14, 82-86. Go to original source... Go to PubMed...
    7. Maneiro, E., Andres de M. C.: Clin. Exp. Rheumatol., 2004; 22, 307-312.
    8. Sobotka, L.: Sestra, 2004; 6, 20-21.
    9. Chen, J. W. Y., Abatangelo, G.: Wound Rep. Reg., 1999; 7, 79-89. Go to original source... Go to PubMed...
    10. Laurent, T. C.: Acta. Otolaryngol., 1987; 442, 7-24. Go to original source... Go to PubMed...
    11. Nimrod, A., Elchanan, E., Ezov, N.: J. Ocul. Pharmacol. TH., 1992; 8, 161-172. Go to original source... Go to PubMed...
    12. Cohen, M., Klein, E., Addadi, L.: In: Hyaluronan 2003 (The Cleveland Clinic Foundation and Matrix Biology Institute, Eds.), Cleveland 2003, s. 10.
    13. Fraser, J. R. E., Laurent, T. C.: In: The biology of hyaluronan (John Wiley & sons eds.) Chirchester, Ciba foundation 1989, s. 41-53.
    14. Reed, R. K., Lilja, K., Laurent, T. C.: Acta. Physiol. Scand., 1988; 134, 405-411. Go to original source... Go to PubMed...
    15. Laurent, T. C.: Acta Otolaryngol., 1987; 442, 7-24. Go to original source... Go to PubMed...
    16. Sakai, S., Yasuda, R., Sayo, T.: J. Invest. Dermatol., 2000; 114, 1184-1187. Go to original source... Go to PubMed...
    17. Komatsu, S., Iwata, H., Nabeshima, T.: Arzneim.Forsch., 1999; 49, 427-433. Go to original source... Go to PubMed...
    18. Zhong, S. P., Campoccia, D., Doherty, P. J.: Biomaterials., 1994; 15, 359-365. Go to original source... Go to PubMed...
    19. Sattar, A., Rooney, P., Kumar, S.: J. Invest. Dermatol., 1994; 103, 576-579. Go to original source... Go to PubMed...
    20. Liu, D., Pearlman, E., Diaconu, E.: Proc. Natl. Acad. Sci., 1996; 93, 7832-7837. Go to original source... Go to PubMed...
    21. Kosaki, R., Watanabe, K., Yamaguchi, Y.: Cancer Res., 1999; 59, 1141-1145.
    22. Sohara, Y., Ishiguro, N., Machida,K.: Mol. Biol. Cell., 2001; 12, 1859-1868. Go to original source... Go to PubMed...
    23. Punzi, L., Pianon, M., Schiavon, F.: In: Redefinig hyaluronan (Abantagelo, G., Weigel, P. H. Eds), Padua, Italy, 1999, s. 137-142.
    24. Prehm, P.: In: Redefinig hyaluronan (Abantagelo, G., Weigel, P. H., Eds), Padua, Italy, 1999, s. 129-135.
    25. Kobayashi, H., Horikoshi, K., Yamataka, A.: J. Pediatr. Surg., 1999; 34, 1791-1794. Go to original source... Go to PubMed...
    26. Duterme, C., Mertens-Strijthagen, J., Flamion, B.: In: Hyaluronan 2003 (The Cleveland Clinic Foundation and Matrix Biology Institute, Eds.), Cleveland 2003, s. 56.
    27. Laurent, T. C., Fraser, J. R. E., Pertoft, H.: Biochem. J., 1986; 234, 653-658. Go to original source... Go to PubMed...
    28. Kensuke, M., Underhill, C. B., Lesley, J.: J. Exp. Med., 1990; 172, 69-75. Go to original source... Go to PubMed...
    29. Day, J. A., Prestwich, G. D.: J. Biol. Chem., 2002; 277, 4585-4588. Go to original source... Go to PubMed...
    30. Turley, E. A., Noble, P. W., Lilly, Y. W.: J. Biol. Chem., 2002; 277, 4589-4592. Go to original source... Go to PubMed...
    31. Lebel, L., Gabrielsson, J., Laurent, T. C.: Eur. J. Clin. Invest., 1994; 24, 621-626. Go to original source... Go to PubMed...
    32. Fraser, J. R. E., Laurent, T. C., Pertoft, H.: Biochem. J., 1981; 200, 415-424. Go to original source... Go to PubMed...
    33. Brown, T. J., Alcorn, D., Robert, J.: J. Invest. Dermatol., 1999; 113, 740-746. Go to original source... Go to PubMed...
    34. Tammi, R., Saamanen Anna-Marja, Maibach, H. I.: J. Invest. dermatol., 1991; 97, 126-130. Go to original source... Go to PubMed...
    35. Laurent, U. B. G., Dahl, L. B., Reed, R. K.: Exp. Physiol., 1991; 76, 695-703. Go to original source... Go to PubMed...
    36. Breborowicz, A., Polubinska, A., Pawlaczyk, K.: Periton. Dialysis Int., 2001; 21, 130-135. Go to original source...
    37. Schauss, A. G., Balogh, L. G., Polyak, A. G.: In: Experimental Biology 2004 - Translating the genom, Washington 2004, Abstract č. 129.4.
    38. Lebel, L., Fraser, J. R., Kimpton, W. S.: Pharm Res., 1989; 6, 677-682. Go to original source... Go to PubMed...
    39. Fraser, J. R. E., Appelgren, Lars-Erik, Laurent, T. C.: Cell Tissue Res., 1983; 233, 285-293. Go to original source... Go to PubMed...
    40. Smedsrod, B., Pertoft, H., Eriksson, J.: Biochem. J., 1984; 223, 617-626. Go to original source... Go to PubMed...
    41. Knudson, W., Peterson, R. S., Embry, J. J.: In: Hyaluronan 2003 (The Cleveland Clinic Foundation and Matrix Biology Institute, Eds.), Cleveland 2003, s. 48.

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