JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2004, 53(6):300-303

Carbomers and Their Use in Pharmaceutical Technology

M. Rabišková1, M. Sedláková1, M. Vítková2, M. Kuna1
1 Ústav technologie léků Farmaceutické fakulty Veterinární a farmaceutické univerzity, Brno
2 Katedra galenickej farmácie Farmaceutickej fakulty Univerzity Komenského, Bratislava

Carbomers, high-molecular polymers based on acrylic acid, are employed in the technology of drugsas auxiliary substances acting as emulsifiers, gel-forming substances, stabilizers of suspensions, andbinders in tablets. Their properties are utilized to control release as well as to improve biologicalavailability of drugs. They are physiologically inert, non-sensitizing, and possess excellent thermalstability. They are used for various routes of administration: topical, oral and peroral, vaginal andrectal.

Keywords: carbomers; auxiliary substances; dosage forms; properties; use

Published: June 1, 2004  Show citation

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Rabišková M, Sedláková M, Vítková M, Kuna M. Carbomers and Their Use in Pharmaceutical Technology. Čes. slov. farm. 2004;53(6):300-303.
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