JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2004, 53(3):131-134

Ricin - A Plant Toxin with Possible Therapeutic Use

M. Nagy
Katedra farmakognózie a botaniky Farmaceutickej fakulty Univerzity Komenského, Bratislava

Ricin is a very toxic RIP II type lectin.As no effective antidote is known, its toxicity could be misusedin terrorist actions. The mechanism of the toxic action is currently studied for the preparation ofselective immunotoxins, which could be used in the therapy of various cancer diseases or HIVinfection. There are promising in vitro results, but some adverse in vivo effects limit the use of thesepreparations in real therapy.

Keywords: ricin; Ricinus communis; toxin; monoclonal antibody

Published: March 1, 2004  Show citation

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Nagy M. Ricin - A Plant Toxin with Possible Therapeutic Use. Čes. slov. farm. 2004;53(3):131-134.
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