Čes. slov. farm. 2004, 53(1):35-38
Selection of the Extraction Agent and the Elaboration of the Technology of the Production of an Extract with a Sedative Effect
- 1 Katedra technologie léků a OF Farmaceutické fakulty Kaunasské univerzity medicíny, Kaunas, Litevská republika
- 2 Katedra farmaceutické chemie a farmakognozie Farmaceutické fakulty Kaunasské univerzity medicíny, Kaunas, Litevská republika
The drugsValerinae radix, Crataegi fructus,Leonuri herba and Melissae folium were used to producea liquid plant extract. The experiment revealed that the extraction with 70% ethanol achieved thehighest concentration of extractable active principles. The optimal conditions for obtaining a sedativeextract are established when the method of repercolation is used, and in the production itselfthe batch of the drug is divided into equally large doses and a pre-prepared mixture of plant drugsis extracted. The extract prepared by this manner remains stable for the whole period of storage,i.e., 24 months.
Keywords: Valerianae radix; Crataegi fructus; Leonuri herba; Melissae folium; plant extract
Published: January 1, 2004 Show citation
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Savickas A, Ramanauskiene K, Savickiene N, Kazlauskas S, Masteiková R, Chalupová Z. Selection of the Extraction Agent and the Elaboration of the Technology of the Production of an Extract with a Sedative Effect. Čes. slov. farm. 2004;53(1):35-38.