JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 1999, 48(4):179-182

Isotachophoretic Analysis of Ophthalmic Drops

I. Valášková, R. Adamčová, B. Boháčová, E. Havránek
Katedra farmaceutickej analýzy a nukleárnej farmácie Farmaceutickej fakulty UniverzityKomenského, Bratislava

The method of capillary isotachophoresis was employed to analyse the active ingredients in theophthalmic drops Tetrakain 0.5% and Atropin 1%. A method has been worked out which representssimplification and increases selectivity in comparison with titration determination according PhBs 4.The pre-adjustment of samples only consists in necessary dilution with demineralised water, thelength of determination not exceeding ten minutes. The method was applied to the investigation ofstability of eye drops.

Keywords: tetracainium chloride; atropinium sulfate; ophthalmic drops; capillary isotachophoresis

Published: April 1, 1999  Show citation

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Valášková I, Adamčová R, Boháčová B, Havránek E. Isotachophoretic Analysis of Ophthalmic Drops. Čes. slov. farm. 1999;48(4):179-182.
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