Pharmaceutical care in self-medication: ABC/VED analysis of over-the-counter antiallergic medicines Viktoriia Oleksiivna Shapovalova¹, Oleksandr Ananiyovych Nevzhoda², Alina Olexandrivna Osyntseva³, Valentyn Valeriiovych Shapovalov¹, Valerii Volodymyrovych Shapovalov³ ¹Soukromá vědecká instituce „Výzkumná univerzita medicínského a farmaceutického práva“, Kyjev, Ukrajina 1Private Scientific Institution “Scientific and Research University of Medical and Pharmaceutical Law”, Kyiv, Ukraine ²Národní lékařská univerzita Danylo Halytskyi Lvov, Lvov, Ukrajina 2Danylo Halytsky Lviv National Medical University, Lvov, Ukraine ³Soukromá vysoká škola Lviv Medical University, Lvov, Ukrajina 3Lviv Medical University, Lviv, Ukraine Introduction: The growing prevalence of allergic diseases and the widespread use of over-the-counter (OTC) medicines necessitate rationalization of symptomatic treatment, balancing clinical relevance with limited healthcare resources. Aim: To evaluate OTC medicines used for symptomatic allergy treatment through ABC/VED analysis in order to identify priority medicines and support pharmaceutical and managerial decision-making. Materials and methods: The study included 25 OTC medicines registered in Ukraine for symptomatic allergy treatment during 2024–2025. Aggregate sales data from pharmacy networks and distributors were analysed. ABC analysis was used to assess expenditure distribution, while VED analysis classified medicines according to clinical importance based on pharmacist protocols, clinical guidelines, pharmacological role, safety profile, and suitability for self-medication. The integrated PLNÁ VERZE ČLÁNKU➜ https://doi.org/10.36290/csf.2026.024 POUZE PRO PŘEDPLATITELE ČASOPISU ČESKÁ A SLOVENSKÁ FARMACIE Justification of a medicinal form development based on the api dimethylammonium 3-methyl-2-(2-((e)-styryl)quinazolin-4-ylthio) butanoate with hepatoprotective and antioxidant effects for the needs of military medicine Antonina Avramenko¹, Andrii Kaplaushenko¹, Volodymyr Salionov² ¹Department of Physical, Colloidal, and Analytical Chemistry, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine ²Department of Clinical Laboratory Diagnostics and Biochemistry, Zaporizhzhia State Medical and Pharmaceutical University, Ukraine Objective: The study aims to substantiate the development of an oral dosage form for military medicine based on the API dimethylammonium 3-methyl-2-(2-((E)-styryl)quinazolin-4-ylthio)butanoate, which demonstrates antioxidant and hepatoprotective activity. The molecule’s physicochemical properties and dissociation constant were evaluated. Materials and Methods: Computer modelling was used to assess lipophilicity, physicochemical parameters, and ADME characteristics via the SwissADME service. Drug-likeness was evaluated according to Lipinski’s Rule of Five. Conductometric PLNÁ VERZE ČLÁNKU➜ https://doi.org/10.36290/csf.2026.023 POUZE PRO PŘEDPLATITELE ČASOPISU ČESKÁ A SLOVENSKÁ FARMACIE
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