JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2016, 65(1):10-14 | DOI: 10.36290/csf.2016.002

Antimicrobial, antiparasitic and anticancer properties of Hibiscus sabdariffa (L.) and its phytochemicals: in vitro and in vivo studies

Sherif T. S. Hassan1,2,*, Katefiina Berchová2, Miroslava Šudomová3
1 Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
2 Department of Applied Ecology, Faculty of Environmental Sciences, Czech University of Life Sciences, Prague, Czech Republic
3 Department of Archeology and Museology, Faculty of Arts, Masaryk University, Brno, Czech Republic

In the last few decades, Hibiscus sabdariffa L. (Malvaceae; H. sabdariffa) has gained much attention in research field because of its potentially useful bioactivity as well as a great safety and tolerability. For decades, microbial, parasitic and cancer diseases remain a serious threat to human health and animals as well. To treat such diseases, a search for new sources such as plants that provide various bioactive compounds useful in the treatment of several physiological conditions is urgently needed, since most of the drugs currently used in the therapy have several undesirable side effects, toxicity, and drug resistance. In this paper, we aim to present an updated overview of in vitro and in vivo studies that show the significant therapeutic properties of the crude extracts and phytochemicals derived from H. sabdariffa as antimicrobial, antiparasitic, and anticancer agents. The future directions of the use of H. sabdariffa in clinical trials will be discussed.

Keywords: Hibiscus sabdariffa L.; antimicrobial agents; cancer preventive agents; antiparasitic drugs; natural products
Grants and funding:

This study was funded by Internal Grant Agency (IGA) of the Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Czech Republic. Project No. 20154247/2015.

Received: November 25, 2015; Accepted: December 16, 2015; Published: January 1, 2016  Show citation

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Hassan STS, Berchová K, Šudomová M. Antimicrobial, antiparasitic and anticancer properties of Hibiscus sabdariffa (L.) and its phytochemicals: in vitro and in vivo studies. Čes. slov. farm. 2016;65(1):10-14. doi: 10.36290/csf.2016.002.
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