JOURNAL OF THE CZECH PHARMACEUTICAL SOCIETY AND THE SLOVAK PHARMACEUTICAL SOCIETY

Čes. slov. farm. 2006, 55(6):268-271

Liquid Ginger Extract: Technology of Production and Quality Evaluation

R. Masteiková1, R. Bernatonienė2, A. Savickas3, Z. Chalupová1, J. Bernatonienė3
1 Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ústav technologie léků
2 Kaunasská univerzita medicíny Litva, Farmaceutická fakulta, Katedra farmaceutické chemie a farmakognozie
3 Kaunasská univerzita medicíny Litva, Farmaceutická fakulta, Katedra technologie léků a sociální farmacie

The paper aimed to elaborate the technology of the production of a liquid ginger extract and to select and verify the methods of quality evaluation of the final preparation. The experiment revealed 70% ethanol as a suitable extraction agent. The optimal conditions for the development of an extract of good quality are established when the herbal drug is crushed to form particles passing through a sieve with a mesh size of 4000 μm, the extraction method is repercolation with the division of the charge of the drug in the relation 5:3:2, and the liquid flows from the percolator at a rate of 0.2ml/min/100 g of the drug. The presence of amino acids, saccharides, glycosides, reducing agents, phenolic substances, and alkaloids in the finished extract was demonstrated by means of colour or precipitation reactions. Thin-layer chromatography was employed to demonstrate gingerols and shogaols. Evaporation residue, ethanol concentration, and the amount of essential oils were determined quantitatively.

Keywords: Zingiber officinale; liquid extract; technology; evaluation

Received: August 2, 2006; Accepted: September 8, 2006; Published: June 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Masteiková R, Bernatonienė R, Savickas A, Chalupová Z, Bernatonienė J. Liquid Ginger Extract: Technology of Production and Quality Evaluation. Čes. slov. farm. 2006;55(6):268-271.
Download citation

References

  1. WHO monographs on selected medicinal plants. Vol. 1. Geneva, WHO, 1999, s. 277.
  2. Vasala, P. A.: In Handbook of herbs and spices (Peter K.V. ed.). Boca Raton, CRC Press, 2001, s. 195. Go to original source...
  3. Langer, E., Greifenberg, S., Gruenwald, J.: Adv. Ther., 1998; 57, 1221-1227.
  4. Ghayur, M. N., Gilani, A. H.: Digest. Diseases Sci., 2005; 50, 1889-1897. Go to original source... Go to PubMed...
  5. Chrubasik, S., Pittler, M. H., Roufogalis, B. D.: Phytomedicine, 2005; 12, 684-701. Go to original source... Go to PubMed...
  6. Ernst, E., Pittler, M. H.: Br. J. Anaest., 2000; 65, 367-371. Go to original source... Go to PubMed...
  7. Chalyakunapruk, N. et al.: Am. J. Obst. Gynecol., 2006; 194, 95-99. Go to original source... Go to PubMed...
  8. Scurr, J. H., Gulati, O. P.: Phytother. Res., 2004, 18, 687-695. Go to original source... Go to PubMed...
  9. Grzanna, R., Lindmark, L., Frondoza, C. G.: J. Medic. Food, 2005; 8, 125-132. Go to original source... Go to PubMed...
  10. Mahady, G. D. et al.: Anticancer Res., 2003; 23, 36993702.
  11. Jolad, S. D. et al.: Phytochemistry, 2005; 66, 1614-1635. Go to original source... Go to PubMed...
  12. Ghayur, M. N., Gilani, A. H.: J. Cardiovasc. Pharmacol., 2005; 45, 74-80. Go to original source... Go to PubMed...
  13. Thomson, M. et al.: Prostagl. Leukotrien. Essent. Fatty Acids, 2002; 67, 475-478. Go to original source... Go to PubMed...
  14. Srinivasan, K.: Int. J. Food Sci. Nutr., 2005; 56, 399-414. Go to original source... Go to PubMed...
  15. Surh,Y.-J.: Food Chem. Toxicol., 2002; 40, 1091-1097. Go to original source... Go to PubMed...
  16. Zancan, K. C. et al.: J. Supercritical Fluids, 2002; 24, 57-76. Go to original source...
  17. Wei, Q.-Y. et al.: J.Ethnopharmacol., 2005; 102, 177-184. Go to original source... Go to PubMed...
  18. Altman, R. D., Marcussen, K. C.: Arthritis Rheum., 2001; 48, 2531-2538. Go to original source...
  19. European Pharmacopoeia 5th Edition. Strasbourg, Council of Europe, 2005.
  20. Savickas, A. et al.: Čes. slov. Farm., 2004; 53, 35-38. Go to original source...
  21. Vetchý, V. et al.: Chem. Listy, 2006; 100, 24-29.
  22. Joland, S. D. et al.: Phytochemistry, 2004; 65, 19371954.




Czech and Slovak Pharmacy

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.